In the natural world, reproductive isolation is a prevalent and fascinating phenomenon that acts as a boundary, separating different species and maintaining the order and diversity of the biological realm. For instance, horses and donkeys, which share some similarities in appearance, can hybridize to produce mules. However, mules are almost infertile and unable to reproduce their own offspring. Similarly, lions and tigers, two majestic large felines, can produce ligers or tigons under specific circumstances, but these hybrid offspring often face numerous health issues, have a difficult survival, and most of them do not possess normal reproductive capabilities. The fundamental reason behind these phenomena is the significant genetic differences between different…