The global Methotrexate market represents a critical pharmaceutical sector with an estimated value of US$532.4 million in 2022, projected to reach US$624.6 million by 2028, growing at a CAGR of 2.7% 1. This essential medication serves dual therapeutic applications in oncology treatment (particularly for leukemia, lymphoma, and breast cancer) and autoimmune disease management (including rheumatoid arthritis and psoriasis). The market encompasses both branded and generic formulations, with tablets and injections comprising the primary dosage forms. North America dominates as the largest market with approximately 49% share, followed by China at 12%, while Indian manufacturers have emerged as significant global suppliers of cost-effective alternatives 1. This comprehensive guide examines the key…