According to a report by WHO, 50% of patients in the world fail to use drugs correctly, and irrational drug use has become the world’s fourth killer. 5 aspects to determine whether clinical use
rational
clinical use of drugs mainly refers to the clinical course of treatment, the use of drugs should be suitable for clinical needs of the patient, the drug dose and treatment should be in line with the actual situation of the patient, the drug cost basis to ensure the efficacy of the Should be the lowest.
Based on the explanation of clinical rational use of drugs, we can judge whether the clinical use of drugs is reasonable from the following aspects:
First, whether the selected drugs are consistent with the patient’s symptoms. This is the primary factor in judging whether clinical medication is reasonable, that is, the choice of medication should be based on the patient’s symptoms.
Second, whether the selected drugs meet the effective, appropriate, safe and economical factors. Effective means that the therapeutic effect of the selected drug has good expectations; safety mainly means that the therapeutic effect of the drug is greater than the risk that the patient bears; appropriate mainly means that the drug dosage, route of administration, and treatment schedule should be reasonable; economy is guaranteed On the basis of the treatment effect, the cost should be reduced as much as possible to reduce the economic burden of the patient.
Third, patients should have no contraindications to the use of drugs, and try to minimize adverse reactions after taking the drugs.
Fourth, whether the usage, dosage and course of treatment are consistent with the actual situation of the patient. That is to say, the dosage of the drugs used, the method of administration, and the course of drug treatment must be consistent with the patient’s condition.
Fifth, patients should have good compliance with the drugs they choose. Three typical manifestation of irrational drug use
in real life, the phenomenon of irrational drug use abound. To sum up, there are three typical irrational medications:
Incorrect medication is one of the important manifestations of irrational medication. For example, the patient’s disease is caused by bacterial infection, and antibiotics should be used for treatment at this time. The choice of antibiotics should be based on the drug sensitivity of the bacteria. If the sensitivity is not high, it is difficult to achieve the expected effect. This kind of situation is the wrong medication; or the abuse of antibiotics, for example, the patient is only treated with antibiotics because of a mild or virus-induced cold, which is also a wrong medication. Fortunately, after years of popular science education, the abuse of antibiotics has gradually decreased. According to the National Medical Service and Quality Safety Report 2018, the use rate of prescription antibacterial drugs in outpatient clinics in my country has dropped from 17.2% in 2011 to 8.9% in 2018, and the use rate of antimicrobial drugs in hospitalized patients has dropped from 61.4% in 2011. This dropped to 40.4% in 2018.
The use of drugs with ineffective or unknown efficacy, such as long-term use of vitamin supplements for patients who have no symptoms of vitamin deficiency, and long-term use of nutritional supplements for patients without obvious malnutrition, are all ineffective drugs.
The use of unsafe drugs mainly refers to the use of drugs that are less effective than drugs. For example, to promote the growth and development of children, the use of anabolic steroids for children; the use of drugs with potential risks such as Analgin for patients with mild colds.
Irrational drug use consequences are serious
delays in the clinical course of the disease therapy, medication unreasonable if you can not achieve the desired effect, resulting in the patient’s condition is delayed or is not controlled, severe cases may endanger the lives of patients. For example, for patients with acute diarrhea and dehydration, wrongly using a large number of antibacterial drugs for treatment, neglecting appropriate salt supplementation, may lead to dehydration and death.
Drugs with adverse reactions have corresponding scope of application, contraindications and adverse reactions. If the drugs used in the treatment process are unreasonable, it may lead to unexpected adverse reactions after the patient’s medication. For example, too much intramuscular injection may cause muscle cramps in the patient. The United States Pharmaceutical Research Institute reported: 3.7% of patients experienced clinically related adverse reactions, of which 20% were drug-related. If 4 or more drugs are used, adverse reactions will increase exponentially.
Increasing the economic burden of patients In the course of clinical treatment, if the medication is unreasonable, it will inevitably prolong the treatment time of patients and increase the types of drugs used by patients, which will increase the cost of medicine and increase the economic burden of patients. It is also a heavy burden for the national healthcare system. Burden. At the same time, unreasonable medication will also cause a waste of medical resources.
