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Oxytetracycline CAS 79-57-2: A Broad-Spectrum Antibiotic from Henan Haitian Biotechnology Co Ltd

Oxytetracycline CAS 79-57-2: A Broad-Spectrum Antibiotic from Henan Haitian Biotechnology Co Ltd
Oxytetracycline CAS 79-57-2 is a broad-spectrum antibiotic produced by Henan Haitian Biotechnology Co Ltd. It is effective against a wide range of bacteria, including Gram-positive and Gram-negative bacteria, mycoplasmas, and rickettsiae. Oxytetracycline is used to treat a variety of infections, including pneumonia, bronchitis, sinusitis, urinary tract infections, and skin infections.

Oxytetracycline is a bacteriostatic antibiotic, which means that it works by preventing bacteria from growing and reproducing. It does this by binding to the 30S ribosomal subunit of bacteria, which prevents the assembly of new ribosomes. This prevents bacteria from synthesizing proteins, which are essential for their growth and survival.

Oxytetracycline is available in a variety of forms, including tablets, capsules, suspensions, and injections. It can be taken orally or administered by injection. The dosage of oxytetracycline will vary depending on the type and severity of the infection being treated.

Synonyms: oxytetracycline, Terramycin, 79-57-2, Oxyterracine, Oxitetracyclin,
Oxytetracyclin:2Z,4S,4aR,5S,5aR,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,6,10,11,12a-pentahydroxy-6-methyl-4,4a,5,5a-tetrahydrotetracene-1,3,12-trione

Application: Oxytetracycline is an antibiotic that impairs mitochondrial protein synthesis
CAS Number:79-57-2

Molecular Weight: 460.43
Molecular Formula: C22H24N2O9

Specification: Injection grade, USP/BP/CP/EP/IP/JP

Oxytetracycline CAS Nr. 79-57-2
Oxytetracycline CAS Nr. 79-57-2

Oxytetracycline is known as a broad-spectrum antibiotic due to its activity against such a wide range of infections. It was the second of the tetracyclines to be discovered. Oxytetracycline, like other tetracyclines, is used to treat many infections common and rare. Its better absorption profile makes it preferable to tetracycline for moderately severe acne, but alternatives sould be sought if no improvement occurs by 3 months.

Oxytetracycline, tetracycline, and chlortetracycline have a low degree of toxicity. Because the tetracyclines are poorly absorbed from the gastrointestinal tract, high concentrations are readily achieved in the intestine, inducing resistant strains, and altering the metabolic activity and colonization resistance properties of the microflora. Selection of resistant bacterial strains appears to be the most sensitive end-point for use in risk assessment, particularly the selection of resistant Enterobacteriaceae. As individuals show little variation with respect to this effect, the Committee concluded that no safety factor was needed and established an ADI of 0-30 µg/kg bw/d (rounded to one significant figure) for the tetracyclines alone or in combination based on the NOEL of 2 mg/d (equivalent to 33 µg/kg bw per day) from a study in humans. Estimated daily intake at the MRLs for tetracyclines, alone or in combination, would be 0.37 mg/p/d.

Physical State :Solid
Solubility :Soluble in DMSO (92 mg/ml at 25° C), water (<1 mg/ml at 25° C), and ethanol (10 mg/ml at 25° C).
Storage :Store at room temperature
Melting Point :184-185° C
Boiling Point :~727.8° C at 760 mmHg (Predicted)
Density :~1.7 g/cm3 (Predicted)
Refractive Index :n20D 1.76 (Predicted)
Optical Activity :α20/D -196.6° in 0.1 N HCl; α20/D -2.1° in 0.1 N NaOH; α25/D +26.5° in methanol
pK Values :pKa: 3.27(25°C)

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