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Diprophylline

Name Diprophylline
Synonyms 7-(2,3-Dihydroxypropyl)theophylline; 7-(2,3-Dihydroxypropyl)-1,3-dimethyl-purine-2,6-dione

Molecular Formula C10H14N4O4
Molecular Weight 254.24
CAS Registry Number 479-18-5
EINECS 207-526-1

Properties
Melting point 160-165 ºC
Water solubility 33 g/100 mL (25 ºC)

Diprophylline or dyphylline, is a xanthine derivative with bronchodilator and vasodilator effects. It is used in the treatment of respiratory disorders like asthma, cardiac dyspnea, and bronchitis. It acts as an adenosine receptor antagonist and phosphodiesterase inhibitor.

Dyphylline has been used in the treatment of acute and chronic bronchial asthma, chronic bronchitis, and emphysema; however, aminophylline, oxtriphylline, and theophylline are considered safer and more effective.

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