Asthma medication, there are priority points

  Asthma is more common in life. It is a chronic inflammatory disease of the airway, which will have a greater impact on the patient’s health and normal life, and may even be fatal. Currently, asthma cannot be cured, but it can be controlled by self-management and scientific medication.
  Based on the patient’s performance, asthma is clinically divided into acute attack period, chronic persistent period, and clinical remission period. The acute attack period refers to the sudden onset of symptoms such as wheezing, shortness of breath, coughing, and chest tightness, or the sharp aggravation of the original symptoms , Often have difficulty breathing and can’t lie down. Doctors call this condition “oriental breathing”. It is often induced by exposure to allergens, irritants or respiratory infections. The severity of the condition varies, and the condition can be aggravated within a few hours or Appears within a few days, and occasionally can be life-threatening within a few minutes; clinical remission refers to the disappearance of the patient’s symptoms and signs after clinical treatment (or no treatment), and the lung function returns to normal levels, and the duration is> 3 months; Chronic duration refers to the different degree and frequency of asthma symptoms that a patient develops every week. Pulmonary function testing can evaluate the degree of on-site control, which can provide a scientific basis for clinical diagnosis.
  The clinical staging of asthma means that the purpose of the medication regimen is different. For patients in the acute stage, “emergency” medication is necessary; for patients with chronic persistence and clinical remission, “pause treatment” is necessary.
  ”Remedy” drugs, simply understood as control drugs that prevent the onset of asthma symptoms. Such drugs are drugs that asthma patients use every day to treat the root cause, and they must be used for a long time regardless of symptoms. Such drugs are mainly inhaled corticosteroids or a combination of inhaled hormones and long-acting β2 receptor agonists. The advantage of inhaled glucocorticoids is that through inhalation, the drug directly acts on the airway mucosa, with strong local anti-inflammatory effects and few systemic adverse reactions. Currently, there are 3 kinds of drugs on the market: beclomethasone propionate, budesonide and fluticasone propionate. The long-acting β2 receptor agonist has a strong and long-lasting effect. It can take up to 10 to 12 hours each time. Combined with glucocorticoids can reduce the dosage of the latter. It has a synergistic effect, is not easy to develop drug resistance, and has cardiovascular effects Extremely small. Commonly used are salmeterol, formoterol, procaterol hydrochloride, and bambuterol.
  The second category is emergency medicine. This type of medicine is used temporarily when an asthma attack becomes worse. It is simply understood as an emergency medicine after an asthma attack. Because asthma attacks are unpredictable, at any time and any place, when patients are exposed to predisposing factors, they may have an acute attack, with obvious coughing and wheezing suddenly, and even life-threatening symptoms when the symptoms are severe. Such drugs mainly include quick-acting or intermediate-acting β2 receptor agonists, such as salbutamol, terbutaline, clenbuterol, and inhaled dosage forms of fenoterol.
  It needs to be emphasized that long-term, single-drug use of short-acting β2 receptor agonists can cause the down-regulation of cell membrane β2 receptors, which manifests as clinical drug resistance. Long-term, single use should be avoided. Therefore, emergency medicine should only be used when asthma is acute. However, the more emergency drugs are used in the course of asthma treatment, the worse the level of disease control will be, and the treatment effect will be insufficient. If the therapeutic effect is definite, the use of alleviating drugs will become less and less or even unnecessary. Asthma patients with the above two types of drugs should be carried with them, usually a combination of the two can better control asthma. But be aware that hypokalemia may occur during critical asthma or acute asthma attacks. Glucocorticoids and diuretics can aggravate the risk of hypokalemia, so patients with combined medications need to monitor blood potassium levels before, after and during medication. For patients with poor control of asthma using inhaled hormones alone, there are other drugs that can be used in combination, such as leukotriene receptor antagonists (montelukast, pranlukast and zalukast), theophylline ( Aminophylline, doxofylline, etc.).
  In addition, it should be noted that some drugs can induce or promote asthma, such as β-blockers, aspirin, penicillin, sulfonamides and other antibacterial drugs and contrast agents. Asthma patients should be used with caution. In daily life, patients with asthma should pay attention to the improvement of their home environment, open windows in time to ventilate, ensure smooth air circulation, expose to more sunlight, keep warm in autumn and winter, avoid cold, try not to contact allergens, choose jogging, yoga, Tai Chi or Swimming and other aerobic exercises that you are interested in can enhance your physique, but be careful not to over-exercise.