New crown vaccine can also prevent other coronaviruses

According to a recent report by the physicist organization network, a study by Northwestern University School of Medicine in the United States has shown for the first time that vaccination with a certain type of coronavirus vaccine and previous infection with a certain type of coronavirus can provide broad immunity against other similar coronaviruses. This latest discovery is for research and development. The release of a universal coronavirus vaccine laid a theoretical foundation, which will help people cope with future epidemics.

Pablo Penaloza McMaster, assistant professor of microbiology and immunology at Northwestern University’s Feinberg School of Medicine, said: “Previously, we didn’t know whether exposure to one coronavirus could provide cross-over against other coronaviruses. Protection, now we have proven it.”

The researchers explained that the three major coronaviruses that currently cause human diseases are the original Sabe virus-including severe acute respiratory syndrome (SARS) virus and new coronavirus, the virus that usually causes the common cold, OC43, and the Middle East Respiratory Syndrome (MERS) virus.

In the latest research, they found that the antibodies produced in the plasma of humans vaccinated with the new crown vaccine have cross-reactivity (providing protection) against SARS virus and OC43. Moreover, the immune response of mice vaccinated with SARS-CoV-1 will protect them from the new coronavirus. The study finally found that a previous infection with a certain type of coronavirus can prevent subsequent infections with other coronaviruses.

Researchers have also found that mice vaccinated with the new coronavirus vaccine, exposed to the common cold coronavirus (HCoV-OC43, which is different from the SARS virus), can partially resist the common cold, but this protection effect is much weaker because of SARS The virus and the new coronavirus are genetically similar, while the common cold coronavirus is more different from the new coronavirus.

Penaloza McMaster said: “As long as the correlation of the coronavirus is greater than 70%, the mice are protected. If they are exposed to very different coronaviruses, the protective effect of the vaccine may be weakened.”

Penaloza McMaster said: “This latest research helps us re-evaluate the concept of a universal coronavirus vaccine. It is likely that there will not be a vaccine for all coronaviruses, but we may end up The main “family” has developed a universal vaccine, such as a universal vaccine against SARS virus, new coronavirus and other SARS-related coronaviruses; or a universal vaccine against HCoV-OC43 and HKU1 that cause the common cold.”

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