Elephant fights cancer

  Elephants are currently the largest mammals on land in the world. They are huge in size and can weigh more than tons. The number of cells is beyond our estimation.
  In general, the greater the number of cells, the greater the probability that the cells will develop lesions, making the body more susceptible to cancer.
  But according to statistics, the incidence of cancer in elephants is less than 5%, and for elephants, the incidence of small human cancers is as high as 20%! What protects most elephants from the “poisonous hands” of cancer?
  Huge size was actually anti-cancer magic
  we first look at how the body will suffer from cancer. First of all, the root cause of cancer is the birth of cancer cells, but the body does not develop disease immediately after the birth of cancer cells.
  Cancer cells are normal cells that are “muted” and have strong instability. They can not only proliferate indefinitely, but also metastasize and destroy normal cells. After the birth of cancer cells, proliferation and metastasis will occur. In this process, some cancer cells will be killed by the body’s immune cells, while some surviving cancer cells will gather together to form a tumor visible to the naked eye. Will be sick.
  Generally speaking, the larger the body, the larger the tumor can make the body ill. If the tumor that can cause human disease is the size of table tennis, then if elephants are to develop disease, cancer cells may need to form tumors the size of basketball.
  It takes longer for cancer cells to form larger tumors. During this time, cancer cells will always be “killed” by the body’s immune system, and the longer the time, the more cancer cells die, and eventually the cancer cells may be completely eliminated by the immune system, making it difficult to form large tumors. Therefore, elephants are less susceptible to disease than humans.
  Activate two-pronged repair
  in addition to the huge stature, the elephant in vivo gene also has a special guard teams, which are 20 p53 gene.
  The P53 gene is a specific tumor suppressor gene and is known as the “guardian of genes”. This gene can detect whether the cell’s DNA is damaged. If the DNA is damaged, it can cause cytopathy and generate cancer cells.
  The P53 gene is also a “switch” for other repair genes. When it detects damaged DNA, it will activate other genes that can repair damaged DNA when it starts to try to repair it. These activated genes can be repaired with it. Damaged DNA. Not only that, it can also “monitor” cell division, which prevents the cell from continuing to divide and grow when there is a tendency for cells to proliferate indefinitely. If the DNA is severely damaged and the gene cannot repair the DNA of the damaged cell, it will trigger the damaged cell’s own destruction system, forcing the damaged cell to “suicide” before turning into a cancer cell.
  Humans can fight some cancers with just one P53 gene, and elephants with 20 P53 genes have such a low incidence of cancer.
  The death gene is activated
  since the P53 gene is an activating factor that is activated in the end is which genes it? Studies have found that one of them is the LIF6 gene.
  This surprised researchers because the LIF6 gene has been dormant for a long time and was once considered a death gene. Although it is retained in the body’s genome, it cannot be activated and can do nothing.
  The researchers found that the relationship between the P53 gene and the LIF6 gene is similar to that between the treating physician and the attending physician. The P53 gene is responsible for “diagnosing” whether DNA is damaged and communicating the “diagnostic results” to the LIF6 gene and awakening it. After the LIF6 gene was awakened by the P53 gene, it began to analyze the “diagnostic results” and then began to repair the damaged DNA with the P53 gene. If it could not be repaired, it would work with the P53 gene to kill the damaged DNA.
  The elephant’s secret to dealing with cancer is gradually being deciphered by human beings. We may be able to “share” anti-cancer tricks with elephants to help humans overcome cancer.