Poor blood pressure control may be the wrong time for medication

Hypertension must be taken on time. But, do you really eat the antihypertensive drugs?

Focus on controlling two peaks

It is especially important to choose the appropriate medication time. The human body will change its metabolism level according to the biological clock, so even if the same dose of the same drug, the time of taking the drug is different, the body’s reactivity to the drug, the drug effect and the adverse reaction of the drug to the body will be different. Controlling blood pressure is mainly to control two “peaks”. When the average person wakes up and wakes up to 10:00 am, the blood pressure rises. After rising to a certain peak, the temperature gradually decreases in the afternoon. In the evening (17-18), the blood pressure rises again, and then the nighttime blood pressure gradually decreases to a low point.

How to eat high blood pressure drugs?

So, how should the drug be eaten? usually:

1. Taking antihypertensive drugs once a day, taking more medicine at 7:00 in the morning. These drugs have a relatively long duration of action and can be controlled when blood pressure reaches the “morning peak.”

2. Taking antihypertensive drugs twice a day, it is advisable to take the drug at 7:00 am and 4:00 pm, so that the peak time of the drug action coincides with the two peak periods of natural fluctuation of blood pressure.

3. Short-acting antihypertensive drugs taken 3 times a day, the medication time should be waking up in the morning, 1:00 pm, 4:00 pm.

Of course, the situation of each person is different. You can also take 24-hour blood pressure monitoring before taking the medicine to find out your blood pressure peak. Under the guidance of a doctor, take the medicine 1 to 2 hours before the peak, so that the blood pressure control time is even more Targeted and individualized.

If your situation does not allow 24-hour blood pressure monitoring, you can also choose 4 time points in a day, measure blood pressure every 6 hours, and measure for 3 days continuously, you can know your blood pressure fluctuations, so you can infer a medication. time.

Do you need to take medicine before going to bed?

It is worth noting that most people fall asleep at night when their blood pressure drops by about 20% compared with the daytime, so the blood pressure at night is at a low level. If you take antihypertensive drugs before going to bed, it will easily lead to a significant drop in blood pressure, resulting in insufficient blood supply to the organs of the heart, brain, kidney, etc., which will have certain risks.

However, some patients may have elevated blood pressure at night or an increase in blood pressure before taking the drug in the morning. These patients need doctors to individually select the type of medication and the time of medication according to the law of elevated blood pressure.

Therefore, whether or not to take medication before going to bed must be based on blood pressure monitoring to follow the doctor’s advice.

In addition, there is a class of antihypertensive drugs, called α-blockers (such as terazosin and other “oxazosin” drugs), may be used in patients with hypertension with benign prostatic hyperplasia. This medicine can cause orthostatic hypotension (refers to hypotension caused by sudden changes in body position or lack of blood supply to the brain for a long time). Due to more activities during the day, it is low in order to avoid position changes during activities such as standing and walking. Blood pressure, therefore, it is better to take medication before going to bed under the guidance of a physician.