Resveratrol has not been in the public eye for a long time, but every time it appears, it will be labeled with the word “magic”, especially in the advertisements of WeChat business that claim “magic” resveratrol Alcohol has the effects of beautifying, beautifying, helping sleep, especially anti-aging. So, is resveratrol really that amazing?
What is resveratrol
Resveratrol, also known as stilbene triphenol, is a natural polyphenolic substance commonly found in grape skins, peanuts, red wine and many other plants.
In 1940, resveratrol, as a natural plant antitoxin, was first discovered in Veratrum by Japanese scholars. In the 1970s, it was discovered that grapes also contained resveratrol.
In the 1980s, the “French Paradox” reported by a TV program in the United States rewritten the fate of resveratrol: The survey found that French people love high-fat foods, but the incidence and mortality of coronary heart disease are significantly lower. In other Western countries, the theory believes that this may be related to the French often drinking wine containing resveratrol. Resveratrol began to enter the public eye.
Not so magical
Many plants containing resveratrol are common medicinal plants themselves, such as Cassia, Veratrum and Polygonum cuspidatum, and some are common foods such as peanuts, grapes and mulberries.
The medical community has also found that resveratrol does have many pharmacological effects, including: ①Neuroprotection, including cerebral ischemia-reperfusion injury protection, improvement of central nervous system degeneration, spinal cord injury protection and anti-epileptic effects, etc.; ②Heart Cerebral vascular protection, including anti-platelet aggregation, anti-atherosclerosis, relaxation and protection of blood vessels, regulation of blood lipids, etc.; ③anti-depression; ④anti-tumor, resveratrol for breast cancer, gastric cancer, colon cancer, prostate cancer, leukemia , Ovarian cancer, skin cancer and other tumors have a certain inhibitory effect; ⑤ anti-oxidation, anti-free radicals; ⑥ anti-inflammatory, anti-bacterial.
However, the research on resveratrol in the medical field is mainly based on cell experiments and animal experiments. So far, no large-scale human trials have been carried out.
The pharmacological effects of resveratrol, coupled with commercial hype, has quickly become a research hotspot in many fields, especially in the field of health preservation such as longevity. In the past 30 to 40 years, there have been tens of thousands of research papers on resveratrol. But in 2012, one of the most influential American professors was proved to be academic fraud, and the efficacy of resveratrol happened to be the focus of his research, and his research results were used extensively in the marketing of related products. During this period, GlaxoSmithKline, a well-known American pharmaceutical company that tried to study human anti-aging drugs, was also forced to terminate the resveratrol research project, because the company discovered in the experiment that resveratrol has a variety of toxic and side effects. Other drug problems.
In summary, although resveratrol may have many pharmacological effects found in cell and animal experiments, due to the obvious differences between different species, resveratrol exhibits pharmacological effects at the cell and animal level. It does not mean that it can also appear in the human body. And in animal experiments, studies on the effects, safety, and side effects of high-dose resveratrol can be carried out, but it is not easy to prove that high-dose, long-term use of the drug is safe and free of side effects on the human body. Therefore, People must be cautious when using resveratrol.